Ethical Considerations of Genome Sequencing for Pediatric Patients

Ethical Considerations of Genome Sequencing for Pediatric Patients
Michelle M Sergi, Melissa C Keinath, Jonathan Fanaroff, Kathryn E Miller
Seminars in Pediatric Neurology, 1 March 2023
Abstract
Advancements in genetic testing in the healthcare setting, most recently genomic sequencing, has enhanced our ability to diagnose genetic conditions. These advances include increased accessibility and affordability of genomic technologies. With expanded use comes the potential for significant ethical challenges for clinicians, particularly considering the implications of testing a child for one condition and incidentally finding a different condition or health risk. In this focused review, we address various ethical considerations from informed consent to the rights of a child undergoing genetic testing.